MARVELD1 Polyclonal Antibody
Product Specifications
Background
MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
GB14; MARVD1; MARVEL (membrane-associating) domain containing 1; MARVEL domain containing protein 1; MRVLDC1; Putative MARVEL domain containing protein 1; MALD1_HUMAN.
Swiss Prot
Q9BSK0
Reactivity
Human, Mouse, Rabbit
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
19 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MARVELD1 Polyclonal Antibody detects endogenous levels of MARVELD1 protein.
Applications Notes
Primary: Anti- MARVELD1 at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
Curated Selection
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