Complement fragment 3c Polyclonal Antibody
Product Specifications
Background
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
AHUS5; acylation-stimulating protein cleavage product; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3; CO3_HUMAN; Complement C3; Complement C3c alpha' chain fragment 2; Complement C3c; Complement component 3; Complement component C3; Complement factor 3; CPAMD1.
Swiss Prot
P01024
Reactivity
Human, Mouse, Rat, Dog, Pig
Immunogen
KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1:1051-1200/1663
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
183 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Complement fragment 3c Polyclonal Antibody detects endogenous levels of Complement fragment 3c protein.
Applications Notes
Primary: Anti-Complement fragment 3c at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
Curated Selection
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