ACPT Polyclonal Antibody
Product Specifications
Background
Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is upregulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. ACPT dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. ACPT is predominantly expressed in testis but exhibits a lower level of expression in testicular cancer tissues than in normal tissues. ACPT has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
Acid phosphatase testicular; Testicular acid phosphatase; PPAT_HUMAN.
Swiss Prot
Q9BZG2
Reactivity
Human, Mouse, Rat, Dog, Horse
Immunogen
KLH conjugated synthetic peptide derived from human ACPT:65-160/437
Conjugation
Unconjugated
Applications
FCM
Dilution
Flow-Cyt=0.2ug/test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
47kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ACPT Polyclonal Antibody detects endogenous levels of ACPT protein.
Host or Source
Rabbit
Available Sizes
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