MCPIP1 Polyclonal Antibody
Product Specifications
Background
Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity) . Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
DJ423B22.1; MCP 1 treatment-induced protein; MCP-induced protein 1; MCPIP 1; MCPIP; Ribonuclease ZC3H12A; RP3-423B22.1; ZC12A_HUMAN; ZC3H 12A; ZC3H12 A; Zc3h12a; Zinc finger CCCH domain-containing protein 12A; Zinc finger CCCH type containing 12A.
Swiss Prot
Q5D1E8
Reactivity
Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human MCPIP1:201-300/599
Conjugation
Unconjugated
Applications
FCM
Dilution
Flow-Cyt=1ug/Test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
66kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MCPIP1 Polyclonal Antibody detects endogenous levels of MCPIP1 protein.
Host or Source
Rabbit
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