ProBNP Polyclonal Antibody

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

BNP 32; BNP (1-28) ; BNP (1-29) ; BNP (1-30) ; BNP (1-32) ; BNP (2-31) ; BNP (3-29) ; BNP (3-30) ; BNP (3-32) ; BNP (4-27) ; BNP (4-29) ; BNP (4-30) ; BNP (4-31) ; BNP (4-32) ; BNP (5-29) ; BNP (5-31) ; BNP (5-32) ; Brain natriuretic peptide 32; Brain type natriuretic peptide; Gamma brain natriuretic peptide; Natriuretic peptide B; Natriuretic peptide brain type; Natriuretic peptide precursor B; natriuretic peptide, brain type; ANFB_MOUSE; Natriuretic peptides B; natriuretic protein; NPPB; NPPB protein.

Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (proBNP) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C