KAT2B Polyclonal Antibody
Product Specifications
Background
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
GCN5; PCAF; CAF; CREBBP associated factor; GCN5; GCN5L; GCN5L1 antibody Histone acetylase PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; K (lysine) acetyltransferase 2B; KAT2B; KAT2B_HUMAN; Lysine acetyltransferase 2B; P antibody P/CAF; p300/CBP associated factor; P300/CBP-associated factor; Pcaf.
Swiss Prot
Q92831
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Horse
Immunogen
KLH conjugated synthetic peptide derived from human KAT2B:451-550/832
Conjugation
Unconjugated
Related Pathways
Nuclear Receptor Signaling, Epigenetic Writers and Erasers of Histone H3, Epigenetic Writers and Erasers of Histones H2A H2B and H4
Applications
FCM
Dilution
Flow-Cyt=1ug/Test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
92kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
KAT2B Polyclonal Antibody detects endogenous levels of KAT2B protein.
Host or Source
Rabbit
Available Sizes
Curated Selection
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