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KAT2B Polyclonal Antibody

Product Specifications

Background

Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

GCN5; PCAF; CAF; CREBBP associated factor; GCN5; GCN5L; GCN5L1 antibody Histone acetylase PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; K (lysine) acetyltransferase 2B; KAT2B; KAT2B_HUMAN; Lysine acetyltransferase 2B; P antibody P/CAF; p300/CBP associated factor; P300/CBP-associated factor; Pcaf.

Swiss Prot

Q92831

Reactivity

Human, Mouse, Rat, Chicken, Dog, Pig, Horse

Immunogen

KLH conjugated synthetic peptide derived from human KAT2B:451-550/832

Conjugation

Unconjugated

Related Pathways

Nuclear Receptor Signaling, Epigenetic Writers and Erasers of Histone H3, Epigenetic Writers and Erasers of Histones H2A H2B and H4

Applications

FCM

Dilution

Flow-Cyt=1ug/Test

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

92kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

KAT2B Polyclonal Antibody detects endogenous levels of KAT2B protein.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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