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PER-3 Polyclonal Antibody

Product Specifications

Background

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. [provided by RefSeq, Jul 2008]

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

2810049O06Rik; Cell growth inhibiting gene 13 protein; Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3; GIG13; gPER3; HGNC:8847; hPER3; mPer3; Per3; PER3_HUMAN; Period circadian protein homolog 3; Period homolog 3 (Drosophila) ; Period homolog 3; Period homolog 3, Drosophila; Period3.

Swiss Prot

P56645

Reactivity

Human, Mouse, Rat

Immunogen

KLH conjugated synthetic peptide derived from human PER-3:101-200/1201

Conjugation

Unconjugated

Applications

IHC-P

Dilution

IHC-P=1:100-500

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~132kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -67°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PER-3 Polyclonal Antibody detects endogenous levels of PER-3 protein.

Applications Notes

Paraformaldehyde-fixed, paraffin embedded (mouse intestine) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PER-3) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C

Host or Source

Rabbit

Available Sizes

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