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TBRG1 Polyclonal Antibody

Product Specifications

Background

Acts as a growth inhibitor. Can activate TP53/p53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. There are two isoforms.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

NIAM; Nuclear interactor of ARF and Mdm2; Transforming growth factor beta regulator 1; TBRG1; TBRG-1; TBRG 1; Transforming growth factor beta regulator 1.

Swiss Prot

Q3YBR2

Reactivity

Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit

Immunogen

KLH conjugated synthetic peptide derived from human TBRG1:28-130/411

Conjugation

Unconjugated

Applications

IHC-P

Dilution

IHC-P=1:100-500

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~45kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -64°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

TBRG1 Polyclonal Antibody detects endogenous levels of TBRG1 protein.

Applications Notes

Paraformaldehyde-fixed, paraffin embedded (Human pancreatic carcinoma) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TBRG1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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