TBRG1 Polyclonal Antibody
Product Specifications
Background
Acts as a growth inhibitor. Can activate TP53/p53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. There are two isoforms.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
NIAM; Nuclear interactor of ARF and Mdm2; Transforming growth factor beta regulator 1; TBRG1; TBRG-1; TBRG 1; Transforming growth factor beta regulator 1.
Swiss Prot
Q3YBR2
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human TBRG1:28-130/411
Conjugation
Unconjugated
Applications
IHC-P
Dilution
IHC-P=1:100-500
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
~45kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -64°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TBRG1 Polyclonal Antibody detects endogenous levels of TBRG1 protein.
Applications Notes
Paraformaldehyde-fixed, paraffin embedded (Human pancreatic carcinoma) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TBRG1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C
Host or Source
Rabbit
Available Sizes
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