ALKBH5 Polyclonal Antibody
Product Specifications
Background
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N (6) -methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export and is required for spermatogenesis.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
ABH5; AlkB, alkylation repair homolog 5 (E. coli) ; AlkB, alkylation repair homolog 5; Alkylated DNA repair protein alkB homolog 5; Alpha ketoglutarate dependent dioxygenase alkB homolog 5; OFOXD; OFOXD1; Oxoglutarate and iron-dependent oxygenase domain containing; Probable alpha ketoglutarate dependent dioxygenase ABH5; RNA demethylase ALKBH5.
Swiss Prot
Q6P6C2
Reactivity
Human, Mouse, Rat, Dog, Cow, Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human ALKBH5:1-100/394
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
~40kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -30°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ALKBH5 Polyclonal Antibody detects endogenous levels of ALKBH5 protein.
Applications Notes
Primary: Anti-ALKBH5 at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
Curated Selection
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