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ALKBH5 Polyclonal Antibody

Product Specifications

Background

Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N (6) -methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export and is required for spermatogenesis.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

ABH5; AlkB, alkylation repair homolog 5 (E. coli) ; AlkB, alkylation repair homolog 5; Alkylated DNA repair protein alkB homolog 5; Alpha ketoglutarate dependent dioxygenase alkB homolog 5; OFOXD; OFOXD1; Oxoglutarate and iron-dependent oxygenase domain containing; Probable alpha ketoglutarate dependent dioxygenase ABH5; RNA demethylase ALKBH5.

Swiss Prot

Q6P6C2

Reactivity

Human, Mouse, Rat, Dog, Cow, Rabbit

Immunogen

KLH conjugated synthetic peptide derived from human ALKBH5:1-100/394

Conjugation

Unconjugated

Applications

WB

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~40kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -30°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ALKBH5 Polyclonal Antibody detects endogenous levels of ALKBH5 protein.

Applications Notes

Primary: Anti-ALKBH5 at 1/1000 dilution

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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