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LRTOMT/LRRC51 Polyclonal Antibody

Product Specifications

Background

This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR) -containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012]

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

COMT2; DFNB63; Leucine rich repeat-containing protein 51; Leucine rich transmembrane and 0-methyltransferase domain containing; LRRC51; LRTOMT1; LRTOMT2; Protein LRTOMT1.

Swiss Prot

Q96E66

Reactivity

Human, Mouse, Rat, Dog, hu, mo, rat, dog

Immunogen

KLH conjugated synthetic peptide derived from human LRTOMT/LRRC51:1-100/192

Conjugation

Unconjugated

Applications

WB

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~26 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -13°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

LRTOMT/LRRC51 Polyclonal Antibody detects endogenous levels of LRTOMT/LRRC51 protein.

Applications Notes

Primary: Anti-LRTOMT/LRRC51 at 1/1000 dilution

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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