LRTOMT/LRRC51 Polyclonal Antibody
Product Specifications
Background
This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR) -containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012]
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
COMT2; DFNB63; Leucine rich repeat-containing protein 51; Leucine rich transmembrane and 0-methyltransferase domain containing; LRRC51; LRTOMT1; LRTOMT2; Protein LRTOMT1.
Swiss Prot
Q96E66
Reactivity
Human, Mouse, Rat, Dog, hu, mo, rat, dog
Immunogen
KLH conjugated synthetic peptide derived from human LRTOMT/LRRC51:1-100/192
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
~26 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -13°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LRTOMT/LRRC51 Polyclonal Antibody detects endogenous levels of LRTOMT/LRRC51 protein.
Applications Notes
Primary: Anti-LRTOMT/LRRC51 at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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