LOR/Loricrin Polyclonal Antibody
Product Specifications
Background
This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008]
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
LOR; LOR protein; LORI_HUMAN; Loricrin; LRN; MGC111513; OTTHUMP00000015823
Swiss Prot
P23490
Reactivity
Human, Horse
Immunogen
KLH conjugated synthetic peptide derived from human LOR/Loricrin:251-312/312
Conjugation
Unconjugated
Applications
IHC-P
Dilution
IHC-P=1:100-500
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
~26 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -18°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LOR/Loricrin Polyclonal Antibody detects endogenous levels of LOR/Loricrin protein.
Applications Notes
Paraformaldehyde-fixed, paraffin embedded (human skin) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LOR) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C
Host or Source
Rabbit
Available Sizes
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