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LOR/Loricrin Polyclonal Antibody

Product Specifications

Background

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008]

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

LOR; LOR protein; LORI_HUMAN; Loricrin; LRN; MGC111513; OTTHUMP00000015823

Swiss Prot

P23490

Reactivity

Human, Horse

Immunogen

KLH conjugated synthetic peptide derived from human LOR/Loricrin:251-312/312

Conjugation

Unconjugated

Applications

IHC-P

Dilution

IHC-P=1:100-500

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~26 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -18°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

LOR/Loricrin Polyclonal Antibody detects endogenous levels of LOR/Loricrin protein.

Applications Notes

Paraformaldehyde-fixed, paraffin embedded (human skin) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LOR) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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