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LCLAT1 Polyclonal Antibody

Product Specifications

Background

Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; AGPAT8; ALCAT1; HSRG1849; lclat1; LCLT1_HUMAN; LYCAT; Lysocardiolipin acyltransferase 1; UNQ1849; UNQ1849/PRO3579

Swiss Prot

Q6UWP7

Reactivity

Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep

Immunogen

KLH conjugated synthetic peptide derived from human LCLAT1:261-360/414

Conjugation

Unconjugated

Applications

WB

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~49 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -19°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

LCLAT1 Polyclonal Antibody detects endogenous levels of LCLAT1 protein.

Applications Notes

Primary: Anti-LCLAT1at 1/300 dilution

Host or Source

Rabbit

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