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DIP2B Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

DIP2 homolog B; DIP2; DIP2B_HUMAN; DIP2 disco interacting protein 2 homolog B (Drosophila) ; Disco interacting protein 2 homolog B; FLJ34278; KIAA1463; MGC104005.

Swiss Prot

Q9P265

Reactivity

Human, Mouse, Rat, Dog, Cow, Rabbit

Immunogen

KLH conjugated synthetic peptide derived from human DIP2:25-130/1576

Conjugation

Unconjugated

Applications

IHC-P

Dilution

IHC-P=1:100-500

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

171kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

DIP2B Polyclonal Antibody detects endogenous levels of DIP2B protein.

Applications Notes

Paraformaldehyde-fixed, paraffin embedded (Mouse brain) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DIP2B) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C

Host or Source

Rabbit

Available Sizes

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