DIP2B Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
DIP2 homolog B; DIP2; DIP2B_HUMAN; DIP2 disco interacting protein 2 homolog B (Drosophila) ; Disco interacting protein 2 homolog B; FLJ34278; KIAA1463; MGC104005.
Swiss Prot
Q9P265
Reactivity
Human, Mouse, Rat, Dog, Cow, Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human DIP2:25-130/1576
Conjugation
Unconjugated
Applications
IHC-P
Dilution
IHC-P=1:100-500
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
171kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DIP2B Polyclonal Antibody detects endogenous levels of DIP2B protein.
Applications Notes
Paraformaldehyde-fixed, paraffin embedded (Mouse brain) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DIP2B) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C
Host or Source
Rabbit
Available Sizes
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