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Phospho-GABBR2 (Ser884) Polyclonal Antibody

Product Specifications

Background

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

GABA B Receptor 2 (phospho S884) ; p-GABA B Receptor 2 (phospho S884) ; p-GABBR2 (Ser884) ; GABBR2; GB2; G protein coupled receptor 51; G-protein coupled receptor 51; GAB B R2; GABA B R2; GABA B receptor 2; GABA B RECEPTOR; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABA[[B]]R2; GABAB R2; GABABR 2; GABABR2; GABB R2; GABBR 2; Gabbr2; GABR2_HUMAN; Gamma aminobutyric acid (GABA) B receptor 2; Gamma aminobutyric acid B receptor 2; Gamma aminobutyric acid GABA B receptor 2; Gamma aminobutyric acid type B receptor subunit 2; Gamma-aminobutyric acid type B receptor subunit 2; Gb 2; Gb2; GH07312; GPR 51; GPR51; GPRC 3B; GPRC3B; HG 20; HG20; HRIHFB2099; Metabotropic GABA B receptor subtype 2; OTTHUMP00000021776; OTTHUMP00000063797; R2 SUBUNIT; BcDNA:GH07312; CG6706; CT20836; D GABA[[B]]R2; D Gaba2; FLJ36928.

Swiss Prot

O75899

Reactivity

Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig

Immunogen

KLH conjugated Synthesised phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser884:IN (p-S) PE

Conjugation

Unconjugated

Applications

WB

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Phosphorylation

Molecular Weight

104 kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-GABBR2 (Ser884) Polyclonal Antibody detects endogenous levels of GABBR2 protein only when phosphorylated at Ser884.

Applications Notes

Primary: Anti- phospho-GABBR2 (Ser884) at 1/1000 dilution

Host or Source

Rabbit

Available Sizes

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