Phospho-FHOD1 (Thr1141) Polyclonal Antibody
Product Specifications
Background
The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
FHOD1 (phospho T1141) ; p-FHOD1 (phospho T1141) ; FH1/FH2 domain containing protein; FH1/FH2 domain-containing protein 1; Fhod1; FHOD1_HUMAN; FHOS; FHOS1; Formin homolog overexpressed in spleen 1; Formin homology 2 domain containing 1; Formin homology 2 domain containing protein 1; Formin homology 2 domain-containing protein 1.
Swiss Prot
Q9Y613
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
Immunogen
KLH conjugated synthesised phosphopeptide derived from human FHOD1 around the phosphorylation site of Thr1141:RR (p-T) LK
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Phosphorylation
Molecular Weight
126 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-FHOD1 (Thr1141) Polyclonal Antibody detects endogenous levels of FHOD1 protein only when phosphorylated at Thr1141.
Applications Notes
Primary: Anti- phospho-FHOD1 (Thr1141) at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
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