ZNF318 Polyclonal Antibody
Product Specifications
Background
ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR) -mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
Endocrine Regulatory Protein; HGNC13578; HRIHFB2436; ZFP318; Zinc Finger Protein 318; ZN318_HUMAN.
Swiss Prot
Q5VUA4
Reactivity
Human, Mouse, Rat, Dog, Pig, Horse, Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human ZNF318
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB=1:500-2000 IHC-P=1:100-500
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
125 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ZNF318 Polyclonal Antibody detects endogenous levels of ZNF318 protein.
Applications Notes
Sample: Lymph node (Mouse) Lysate at 40 ug Testis (Mouse) Lysate at 40 ug A549 (Human) Cell Lysate at 30 ug HL60 (Human) Cell Lysate at 30 ug 293T (Human) Cell Lysate at 30 ug Primary: Anti- ZNF318 at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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