What is the catalog number for GRAF Polyclonal Antibody?

The catalog number for GRAF Polyclonal Antibody is BS65676.

What sizes are available for GRAF Polyclonal Antibody?

GRAF Polyclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does GRAF Polyclonal Antibody come in?

GRAF Polyclonal Antibody is available in 2 different pack sizes.

Is GRAF Polyclonal Antibody in stock?

GRAF Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

GRAF Polyclonal Antibody

Product Specifications

Background

Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

Arhgap 26; ARHGAP26; FLJ42530; GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125 (FAK) ; KIAA0621; oligophrenin 1 like protein; Oligophrenin-1-like protein; oligophrenin1like protein; OPHN1L; OPHN1L1; RHG26_HUMAN; Rho GTPase activating protein 26; Rho GTPase activating protein26; Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26.

Swiss Prot

Q9UNA1

Reactivity

Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep

Immunogen

KLH conjugated synthetic peptide derived from human GRAF1

Conjugation

Unconjugated

Applications

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

38 kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

GRAF Polyclonal Antibody detects endogenous levels of GRAF protein.

Applications Notes

Sample: Cerebrum (Rat) Lysate at 40 ug Cerebrum (Mouse) Lysate at 40 ug Cerebellum (Rat) Lysate at 40 ug HepG2 (Human) Cell Lysate at 30 ug Kidney (Rat) Lysate at 40 ug Kidney (Mouse) Lysate at 40 ug A549 (Human) Cell Lysate at 30 ug A431 (Human) Cell Lysate at 30 ug HL60 (Human) Cell Lysate at 30 ug U937 (Human) Cell Lysate at 30 ug Cerebellum (Mouse) Lysate at 40 ug Primary: Anti-GRAF at 1/1000 dilution