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Phospho-DAB2 (Ser24) Polyclonal Antibody

Product Specifications

Background

DAB2 is a component of the CSF1 signal transduction pathway. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines. The down regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2 like domains, alpha and beta) .

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

P-Dab2 (Ser24) ; DAB 2; DAB-2; Differentially expressed protein 2; Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein) ; disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) ; Disabled homolog 2; Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila) ; Disabled homolog 2 mitogen responsive phosphoprotein; disabled homolog 2 mitogen-responsive phosphoprotein (Drosophila) ; DOC 2; DOC2; FLJ26626; Mitogen responsive phosphoprotein; DAB2_HUMAN.

Swiss Prot

P98082

Reactivity

Human, Mouse, Rat, Dog, Pig, Cow

Immunogen

KLH conjugated synthesised phosphopeptide derived from human DAB2 around the phosphorylation site of Ser24

Conjugation

Unconjugated

Applications

FCM

Dilution

Flow-Cyt=1ug/Test

Purity

Affinity purified by Protein A

Modification

Phosphorylation

Molecular Weight

85kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-DAB2 (Ser24) Polyclonal Antibody detects endogenous levels of phospho-DAB2 protein only when phosphorylated at Ser24

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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