FAM71D Polyclonal Antibody

Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The FAM71D gene product has been provisionally designated FAM71D pending further characterization.

C14orf54; Chromosome 14 open reading frame 54; Family with sequence similarity 71, member D; FLJ36130; GARI-L2; Golgi-associated Rab2B interactor-like 2; Hypothetical protein LOC161142; Protein FAM71D; FA71D_HUMAN.