Thyroid peroxidase Polyclonal Antibody

Product Specifications

Background

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

MSA; PERT_HUMAN; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX.

Swiss Prot

P07202

Reactivity

Human, Mouse, Rat

Immunogen

KLH conjugated synthetic peptide derived from human Thyroid peroxidase

Conjugation

Unconjugated

Applications

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

105 kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Thyroid peroxidase Polyclonal Antibody detects endogenous levels of Thyroid peroxidase protein.

Applications Notes

Sample: Lane 1: MCF-7 (Human) Cell Lysate at 30 ug Lane 2: K562 (Human) Cell Lysate at 30 ug Lane 3: A673 (Human) Cell Lysate at 30 ug Lane 4: A431 (Human) Cell Lysate at 30 ug Primary: Anti- Thyroid peroxidase (bs-10406R) at 1/1000 dilution Anti-beta-Actin (bs-0061R) at 1/2000 dilution