Thyroid peroxidase Polyclonal Antibody
Product Specifications
Background
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
MSA; PERT_HUMAN; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX.
Swiss Prot
P07202
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic peptide derived from human Thyroid peroxidase
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
105 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Thyroid peroxidase Polyclonal Antibody detects endogenous levels of Thyroid peroxidase protein.
Applications Notes
Sample: Lane 1: MCF-7 (Human) Cell Lysate at 30 ug Lane 2: K562 (Human) Cell Lysate at 30 ug Lane 3: A673 (Human) Cell Lysate at 30 ug Lane 4: A431 (Human) Cell Lysate at 30 ug Primary: Anti- Thyroid peroxidase (bs-10406R) at 1/1000 dilution Anti-beta-Actin (bs-0061R) at 1/2000 dilution
Host or Source
Rabbit
Available Sizes
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