Phospho-TH (Ser31) Polyclonal Antibody

Product Specifications

Background

Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

Tyrosine Hydroxylase (Phospho-Ser31) ; Dystonia 14; DYT14; DYT5b; EC 1.14.16.2; OTTHUMP00000011225; OTTHUMP00000011226; ple; Protein Pale; TH; The; TY3H_RAT; TYH; Tyrosine 3 hydroxylase; Tyrosine 3 monooxygenase; Tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase.

Swiss Prot

P04177

Reactivity

Mouse, Rat

Immunogen

KLH conjugated synthesised phosphopeptide derived from rat TH around the phosphorylation site of Ser31

Conjugation

Unconjugated

Applications

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Phosphorylation

Molecular Weight

59 kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-TH (Ser31) Polyclonal Antibody detects endogenous levels of Phospho-TH protein only when phosphorylated at Ser31

Applications Notes

Sample: Lane 1: Adrenal gland (Mouse) Lysate at 40 ug Lane 2: Adrenal gland (Rat) Lysate at 40 ug Primary: Anti-Phospho-TH (Ser31) at 1/300 dilution

Host or Source

Rabbit

Available Sizes

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