PNMA3 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

MA3; MA5; MGC132756; MGC132758; Paraneoplastic antigen Ma3; Paraneoplastic cancer testis brain antigen; Paraneoplastic Ma antigen 3; PNMA 3; PNMA3; PNMA3_MOUSE.

Swiss Prot

Q8JZW8

Reactivity

Mouse, Rat

Immunogen

KLH conjugated synthetic peptide derived from mouse PNMA3:351-450/463

Conjugation

Unconjugated

Applications

Dilution

WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~57kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PNMA3 polyclonal Antibody detects endogenous levels of PNMA3 protein.

Applications Notes

Cerebrum (Mouse) Lysate at 40 ug Cerebellum (Mouse) Lysate at 40 ug Primary: Anti-PNMA3 at 1/1000 dilution

Host or Source

Rabbit

Available Sizes

Curated Selection

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