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DNase II polyclonal antibody

Product Specifications

Background

Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

Acid DNase; Deoxyribonuclease 2 alpha; Deoxyribonuclease 2; Deoxyribonuclease II alpha; Deoxyribonuclease II; Deoxyribonuclease II lysosomal; Deoxyribonuclease-2-alpha; Deoxyribonuclease2; DeoxyribonucleaseII; DNASE 2; DNASE 2A; DNase II alpha; DNase II lysosomal; DNASE2; DNASE2A; DNaseII; DNL 2; DNL; DNL2; DNS2A_HUMAN; Lysosomal DNase II; R31240 2; R31240_2.

Swiss Prot

O00115

Reactivity

Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep

Immunogen

KLH conjugated synthetic peptide derived from human DNase II:201-300/360

Conjugation

Unconjugated

Applications

WB

Dilution

WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~45kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

DNase II polyclonal Antibody detects endogenous levels of DNase II protein.

Applications Notes

Anti-DNase II at 1/300 dilution

Host or Source

Rabbit

Available Sizes

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