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Mras polyclonal antibody

Product Specifications

Background

MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

M-RAS; M ras; muscle RAS oncogene homolog precursor; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; RRas3; XRas.

Swiss Prot

O08989

Reactivity

Mouse, Rat

Immunogen

KLH conjugated synthetic peptide derived from mouse MRas:201-259/259

Conjugation

Unconjugated

Applications

WB

Dilution

WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

~21kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Mras polyclonal Antibody detects endogenous levels of Mras protein.

Applications Notes

Anti-MRas at 1/1000 dilution

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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