NHEDC2 Polyclonal Antibody
Product Specifications
Background
Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
NHA2; Mitochondrial Na (+) /H (+) exchanger NHA2; Mitochondrial sodium/hydrogen exchanger NHA2; Na (+) /H (+) exchanger like domain containing protein 2; Na+/H+ exchanger domain containing 2; NHE domain containing protein 2; NHE10; NHEDC 2; Sodium/hydrogen exchanger like domain containing protein 2; SL9B2_HUMAN.
Swiss Prot
Q86UD5
Reactivity
Human, Mouse, Rat, Dog, Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human NHEDC2:151-250/537
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
53 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NHEDC2 Polyclonal Antibody detects endogenous levels of NHEDC2 protein.
Applications Notes
Primary: Anti-NHEDC2 at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
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