RNF128 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
E3 ubiquitin protein ligase RNF128; E3 ubiquitin-protein ligase RNF128; FLJ23516; Gene related to anergy in lymphocytes protein; GRAIL; ring finger protein 128; RN128_HUMAN; RNF128.
Swiss Prot
Q8TEB7
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Zebrafish
Immunogen
KLH conjugated synthetic peptide derived from human RNF128:151-260/428
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB=1:500-2000 IHC-P=1:100-500
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
43kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RNF128 Polyclonal Antibody detects endogenous levels of RNF128 protein.
Applications Notes
Primary: Anti- RNF128 at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
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