SRXN1 Polyclonal Antibody
Product Specifications
Background
Sulfiredoxin, also designated Sulfiredoxin-1 and chromosome 20 open reading frame 139 (C20orf139), is a cytoplasmic antioxidant protein involved in signaling through catalytic reduction of oxidative modifications. It regulates peroxiredoxins (PRXs), a family of proteins that reduce hydroperoxides, by reducing the conserved cysteine from sulfinic to sulfenic acid. This impacts the role of PRX in the reduction of other downstream transcription factors and kinase signaling pathways. The Sulfiredoxin protein specifically acts on the PRDX1, PRDX2, PRDX3 and PRDX4 peroxiredoxins, but not on PRDX5 or PRDX6. Sulfiredoxin acts as a phosphotransferase and an athioltransferase and is widely expressed, with highest levels detected in lung, spleen, kidney and thymus tissues.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
C20orf1392; Chromosome 20 open reading frame 139; dJ850E9.2; Npn3; Npn31; SRX1; SRXN 1; Sulfiredoxin 1; Sulfiredoxin 1 homolog (S. cerevisiae) ; Sulfiredoxin 1 homolog; YKL086W; SRXN1_HUMAN.
Swiss Prot
Q9BYN0
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human SRXN1:45-137/137
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
15 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SRXN1 Polyclonal Antibody detects endogenous levels of SRXN1 protein.
Applications Notes
Primary: Anti-SRXN1 at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
IRBAMLBRCA1AP669200UL 200 µL
Rabbit Anti BRCA1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4) (Western Blot,IHC-p,Immunofluorescence,ELISA) 200ul
Sign In for Pricing
View Details 
MBS1448883-01 0.02 mg (E-Coli)
Recombinant Sodalis glossinidius DNA-directed RNA polymerase subunit alpha (rpoA)
Sign In for Pricing
View Details MBS1448883-02 0.02 mg (Yeast)
Recombinant Sodalis glossinidius DNA-directed RNA polymerase subunit alpha (rpoA)
Sign In for Pricing
View Details MBS1448883-03 0.1 mg (E-Coli)
Recombinant Sodalis glossinidius DNA-directed RNA polymerase subunit alpha (rpoA)
Sign In for Pricing
View Details MBS1448883-04 0.1 mg (Yeast)
Recombinant Sodalis glossinidius DNA-directed RNA polymerase subunit alpha (rpoA)
Sign In for Pricing
View Details