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CCDC12 Polyclonal Antibody

Product Specifications

Background

CCDC12, also known as FLJ39430, FLJ40801 or MGC23918, is a 166 amino acid protein encoded by a gene mapping to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

CAS Number

9007-83-4

Structure Composition

0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Product Name Alternative

CCD12_HUMAN; CCDC12; Coiled coil domain containing 12; Coiled-coil domain-containing protein 12; FLJ39430; FLJ40801; MGC23918.

Swiss Prot

Q8WUD4

Reactivity

Human, Mouse, Rat, Dog, Pig, Cow, Horse

Immunogen

KLH conjugated synthetic peptide derived from human CCDC12:19-120/166

Conjugation

Unconjugated

Applications

WB

Dilution

WB=1:500-2000

Purity

Affinity purified by Protein A

Modification

Unmodification

Molecular Weight

58 kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CCDC12 Polyclonal Antibody detects endogenous levels of CCDC12 protein.

Applications Notes

Primary: Anti-CCDC12 at 1/1000 dilution

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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