SLC34A1 polyclonal antibody

Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals. The brush-border membrane Na+/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na (+) /P (i) cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells . NPT2 gene expression is crucial for PTH effects on renal P (i) handling. However, renal expression of the sodium/phosphate cotransporter gene, NPT2, is not required for regulation of renal 1 alpha-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.

NPT2; SLC17A2; Sodium-dependent phosphate transport protein 2A; Sodium-phosphate transport protein 2A; Na (+) -dependent phosphate cotransporter 2A; NaPi-3; Sodium/phosphate cotransporter 2A; Na (+) /Pi cotransporter 2A; NaPi-2a; Solute carrier family 34 member 1

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .