SLC34A1 polyclonal antibody
Product Specifications
Background
Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals. The brush-border membrane Na+/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na (+) /P (i) cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells . NPT2 gene expression is crucial for PTH effects on renal P (i) handling. However, renal expression of the sodium/phosphate cotransporter gene, NPT2, is not required for regulation of renal 1 alpha-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
NPT2; SLC17A2; Sodium-dependent phosphate transport protein 2A; Sodium-phosphate transport protein 2A; Na (+) -dependent phosphate cotransporter 2A; NaPi-3; Sodium/phosphate cotransporter 2A; Na (+) /Pi cotransporter 2A; NaPi-2a; Solute carrier family 34 member 1
Swiss Prot
Q06495
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human SLC34A1.
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 68 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SLC34A1 polyclonal antibody detects endogenous levels of SLC34A1 protein.
Applications Notes
Western blot analysis of SLC34A1 expression in A549 (A), mouse kidney (B), rat lung (C) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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