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RPGR polyclonal antibody

Product Specifications

Background

Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity) . May be involved in microtubule organization and regulation of transport in primary cilia.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

COD1; Cone Dystrophy 1 (X-Linked) ; CORDX1; CRD; Orf15; PCDX; Retinitis Pigmentosa 15; Retinitis Pigmentosa GTPase Regulator; RP15; RP3; RPGR; RPGR_HUMAN; X-linked retinitis pigmentosa GTPase regulator; XLRP3

Swiss Prot

Q92834

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from Human RPGR (Accession Q92834), corresponding to amino acid residues L986-N1009.

Conjugation

Unconjugated

Applications

WB IHC ELISA

Dilution

WB 1:500-1:2000 IHC 1:50-1:200 ELISA (peptide) 1:20000-1:40000

Purity

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 113 kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RPGR polyclonal antibody detects endogenous levels of RPGR protein.

Applications Notes

Western blot analysis of extracts of Rat testis, using RPGR antibody at 1:500 dilution.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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