RECK polyclonal antibody

Product Specifications

Background

Reversion inducing cysteine rich protein with kazal motifs (RECK) Homo sapiens The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein

Swiss Prot

O95980

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide, corresponding to Human RECK.

Conjugation

Unconjugated

Applications

WB IF ICC

Dilution

WB 1:500 - 1:1000 IF 1:50 - 1:200 ICC 1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 110 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RECK polyclonal antibody detects endogenous levels of RECK protein.

Applications Notes

Western blot (WB) analysis of RECK pAb at 1:500 dilution LaneA:MCF-7 whole cell lysate (40ug) LaneB:The Kidney tissue lysate of Mouse (40ug)

Host or Source

Rabbit

Available Sizes

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