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GLS2 polyclonal antibody

Product Specifications

Background

Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

GA; Glutaminase liver isoform mitochondrial; GLS; L-glutaminase; L-glutamine amidohydrolase

Swiss Prot

Q9UI32

Reactivity

Human, Mouse, Rat

Immunogen

KLH-conjugated synthetic peptide of human GLS2. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB (1/500 - 1/2000), IF/ICC (1/50 - 1/200)

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 65 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of GLS2 protein

Applications Notes

Western blot analysis of GLS2 expression in HEK293T (A), mouse lung (B), rat brain (C) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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