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ERp5 polyclonal antibody

Product Specifications

Background

May function as a chaperone that inhibits aggregation of misfolded proteins.Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling.May also regulate the UPR via the EIF2AK3 UPR sensor.Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

ERP5; P5; TXNDC7; Protein disulfide-isomerase A6; Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7

Swiss Prot

Q15084

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length protein of human ERp5

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB (1/500 - 1/2000), IF/ICC (1/50 - 1/100)

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 48 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of ERp5 protein.

Applications Notes

Western blot analysis of ERp5 expression in SW480 (A), HepG2 (B), mouse lung (C), mouse testis (D), rat liver (E) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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