ERp5 polyclonal antibody
Product Specifications
Background
May function as a chaperone that inhibits aggregation of misfolded proteins.Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling.May also regulate the UPR via the EIF2AK3 UPR sensor.Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
ERP5; P5; TXNDC7; Protein disulfide-isomerase A6; Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7
Swiss Prot
Q15084
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length protein of human ERp5
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB (1/500 - 1/2000), IF/ICC (1/50 - 1/100)
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 48 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of ERp5 protein.
Applications Notes
Western blot analysis of ERp5 expression in SW480 (A), HepG2 (B), mouse lung (C), mouse testis (D), rat liver (E) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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