C4BP beta polyclonal antibody
Product Specifications
Background
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
C4b-binding protein beta chain
Swiss Prot
P20851
Reactivity
Human
Immunogen
Recombinant full length protein of human C4BP beta
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB (1/500 - 1/2000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/100)
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 28 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of C4BP beta protein.
Applications Notes
Western blot analysis of C4BP beta expression in HepG2 (A), mouse testis (B), rat testis (C) whole cell lysates.
Host or Source
Rabbit
Available Sizes
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