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Mammaglobin-A/B monoclonal antibody

Product Specifications

Background

Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.

CAS Number

9007-83-4

Structure Composition

Mouse IgG2a. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Product Name Alternative

LIPHC; MGB2; UGB3; Mammaglobin-B; Lacryglobin; Lipophilin-C; Mammaglobin-2; Secretoglobin family 2A member 1; MGB1; UGB2; Mammaglobin-A; Mammaglobin-1; Secretoglobin family 2A member 2

Swiss Prot

O75556; Q13296

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within human Mammaglobin-A/B. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

IHC

Dilution

IHC (1/100 - 1/300)

Purity

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 10 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of Mammaglobin-A/B protein.

Host or Source

Mouse

Available Sizes

Frequently Asked Questions

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