What is the catalog number for CD35 monoclonal antibody?

The catalog number for CD35 monoclonal antibody is MB66112.

What sizes are available for CD35 monoclonal antibody?

CD35 monoclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does CD35 monoclonal antibody come in?

CD35 monoclonal antibody is available in 2 different pack sizes.

Is CD35 monoclonal antibody in stock?

CD35 monoclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CD35 monoclonal antibody

Product Specifications

Background

Complement receptor type 1` (CR1; CD35) is a type I transmembrane glycoprotein that is expressed on the surface of B cells, neutrophils, monocytes and renal podocytes. As a component of the host innate immune system, CR1/CD35 expressed on neutrophils and monocytes binds to ligands coated with the complement opsonins, C3b and C4b, which facilitates phagocytosis and production of proinflammatory cytokines. CR1/CD35 also participates in negative regulation of the complement cascade through its ability to promote dissociation of C3 and C5 convertases and by serving as one of multiple cofactors for Factor-I-mediated cleavage and inactivation of C3b and C4b.

CAS Number

9007-83-4

Structure Composition

Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Product Name Alternative

C3BR; Complement receptor type 1; C3b/C4b receptor; CD35

Swiss Prot

P17927

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within human CD35. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

IHC

Dilution

IHC (1/100 - 1/300)

Purity

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .