ACP5 monoclonal antibody
Product Specifications
Background
Tartrate-resistant acid phosphatase is an iron containing glycoprotein that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. TRAP is the most basic of the acid phosphatases and is the only form not inhibited by L+-tartrate. TRAP is a relatively minor lysosomal enzyme which may be activated in certain pathologies such as Hodgkin’s disease and B- and T-cell leukemias. Receptor activator of NFκB ligand (RANKL) plays an essential role in osteoclast differentiation and activation by increasing the expression of protease osteoclast markers such as TRAP. TRAP has collagenolytic activity and plays a major role in ligament degradation.
CAS Number
9007-83-4
Structure Composition
Mouse IgG2a. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Product Name Alternative
Tartrate-resistant acid phosphatase type 5; TR-AP; Tartrate-resistant acid ATPase; TrATPase; Type 5 acid phosphatase
Swiss Prot
P13686
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within human ACP5. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC (1/100 - 1/300)
Purity
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 36 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of ACP5 protein.
Host or Source
Mouse
Available Sizes
Curated Selection
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