Kallikrein 3 monoclonal antibody

Product Specifications

Background

Kallikrein 3 (KLK3), also known as Prostate Specific Antigen (PSA), is a member of the glandular kallikrein subfamily of serine proteases. It is produced by prostate epithelial cells and is secreted into prostatic ducts. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer.

CAS Number

9007-83-4

Structure Composition

Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Product Name Alternative

APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase

Swiss Prot

P07288

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within human Kallikrein 3. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

IHC

Dilution

IHC (1/100 - 1/300)

Purity

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .