Factor XIIIa monoclonal antibody
Product Specifications
Background
Factor XIIIA, or fibrin stabilizing factor, is activated by thrombin and Ca2+ to a protransglutaminase in the final step of the blood coagulation cascade that cross-links fibrin chains. This enzyme catalyzes the gamma-glutamyl-epsilon-lysine cross-linking between fibrin molecules, stabilizing the fibrin clot. It is widely expressed in dermal dendritic cells. High expression of Factor XIIIA positive cells can be indicative of inflammatory conditions such as lichen planus and psoriasis.
CAS Number
9007-83-4
Structure Composition
Mouse IgG2a. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Product Name Alternative
F13A; Coagulation factor XIII A chain; Coagulation factor XIIIa; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain
Swiss Prot
P00488
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within human Factor XIIIa. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC (1/100 - 1/300)
Purity
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 83 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of Factor XIIIa protein.
Host or Source
Mouse
Available Sizes
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