What is the catalog number for PARP1 monoclonal antibody?

The catalog number for PARP1 monoclonal antibody is MB65968.

What sizes are available for PARP1 monoclonal antibody?

PARP1 monoclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does PARP1 monoclonal antibody come in?

PARP1 monoclonal antibody is available in 2 different pack sizes.

Is PARP1 monoclonal antibody in stock?

PARP1 monoclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PARP1 monoclonal antibody

Product Specifications

Background

PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved by many ICE-like caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa) . PARP helps cells to maintain their viability; cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD (+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Swiss Prot

P09874

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence of human PARP1. The exact sequence is proprietary.

Conjugation

Unconjugated

Related Pathways

NF-kB Signaling, Death Receptor Signaling

Applications

WB, IHC

Dilution

WB (1/1000 - 1/3000), IHC (1/200 - 1/500)

Purity

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .