ABCB5 monoclonal antibody
Product Specifications
Background
Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:12960149, PubMed:22306008, PubMed:15899824, PubMed:15205344) . Specifically present in limbal stem cells, where it plays a key role in corneal development and repair (By similarity) .
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
ATP-binding cassette sub-family B member 5; ABCB5 P-gp; P-glycoprotein ABCB5
Swiss Prot
Q2M3G0
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence of human ABCB5. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC
Dilution
WB (1/1000 - 1/2000), IHC (1/200 - 1/500)
Purity
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of ABCB5 protein.
Applications Notes
Western blot analysis of ABCB5 expression in Hela (A), 293T (B) whole cell lysates.
Host or Source
Mouse
Available Sizes
Curated Selection
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