IL-4 Rat monoclonal antibody
Product Specifications
Background
Interleukin-4 (IL-4) is a cytokine secreted by activated T cells, basophils, and mast cells. While it contributes to many immunomodulatory responses, it is mainly recognized as the cytokine responsible for eliciting differentiation of naive T cells into Th2 lineage cells that are defined by their secretion of IL-4, IL-5, and IL-10. In addition, IL-4 contributes to immunoglobulin class switching by inducing the production of IgE from B cells. IL-4 acts through the IL-4 receptor, leading to tyrosine phosphorylation and activation of the Stat6 transcription factor.
CAS Number
9007-83-4
Structure Composition
Rat IgG1 kappa. Liquid in PBS, pH 7.3, and 0.02% sodium azide.
Product Name Alternative
Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Swiss Prot
P05112
Reactivity
Human
Immunogen
CHO-expressed recombinant human IL-4
Conjugation
Unconjugated
Applications
IF, FC
Dilution
IF (1/50 - 1/200)
Purity
The monoclonal antibody was affinity-purified from Rat antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 17 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes human IL-4
Host or Source
Rat
Available Sizes
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