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NCOA5 polyclonal antibody

Product Specifications

Background

Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2) .

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

KIAA1637; Nuclear receptor coactivator 5; NCoA-5; Coactivator independent of AF-2; CIA

Swiss Prot

Q9HCD5

Reactivity

Human, Rat, Mouse

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NCOA5. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 204% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 63 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of NCOA5 protein.

Applications Notes

Western blot analysis of NCOA5 expression in mouse muscle (A), rat muscle (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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