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NOX5 polyclonal antibody

Product Specifications

Background

Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

NADPH oxidase 5

Swiss Prot

Q96PH1

Reactivity

Human, Rat

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NOX5. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 203% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 78 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of NOX5 protein.

Applications Notes

Western blot analysis of NOX5 expression in rat kidney (A) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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